scholarly journals Effects of Contaminants on Behavior: Biochemical Mechanisms and Ecological Consequences

BioScience ◽  
2001 ◽  
Vol 51 (3) ◽  
pp. 209 ◽  
Author(s):  
JUDITH S. WEIS ◽  
GRAEME SMITH ◽  
TONG ZHOU ◽  
CELINE SANTIAGO-BASS ◽  
PEDDRICK WEIS
2013 ◽  
Vol 44 (4) ◽  
pp. 72-80
Author(s):  
N. Leus ◽  
◽  
S. Kolomiichuk ◽  
Nizar Boudaya Nizar ◽  
A. Girzheva ◽  
...  

Author(s):  
Sisir Nandi ◽  
Mohit Kumar ◽  
Mridula Saxena ◽  
Anil Kumar Saxena

Background: The novel coronavirus disease (COVID-19) is caused by a new strain (SARS-CoV-2) erupted in 2019. Nowadays, it is a great threat that claims uncountable lives worldwide. There is no specific chemotherapeutics developed yet to combat COVID-19. Therefore, scientists have been devoted in the quest of the medicine that can cure COVID- 19. Objective: Existing antivirals such as ASC09/ritonavir, lopinavir/ritonavir with or without umifenovir in combination with antimalarial chloroquine or hydroxychloroquine have been repurposed to fight the current coronavirus epidemic. But exact biochemical mechanisms of these drugs towards COVID-19 have not been discovered to date. Method: In-silico molecular docking can predict the mode of binding to sort out the existing chemotherapeutics having a potential affinity towards inhibition of the COVID-19 target. An attempt has been made in the present work to carry out docking analyses of 34 drugs including antivirals and antimalarials to explain explicitly the mode of interactions of these ligands towards the COVID-19protease target. Results: 13 compounds having good binding affinity have been predicted towards protease binding inhibition of COVID-19. Conclusion: Our in silico docking results have been confirmed by current reports from clinical settings through the citation of suitable experimental in vitro data available in the published literature.


2020 ◽  
Vol 06 ◽  
Author(s):  
Sayed Md Mumtaz ◽  
Madhu Gupta ◽  
Ramesh K. Goyal

Abstract:: The placenta that maintains and regulates the growth of fetus, consists of various biological treasures nutrients such as cytomedines, vitamins, trace elements, amino acids, peptides, growth factors and other biologically active constituents. Their therapeutic usefulness can well define in the terms of biochemical mechanisms of various components present in it. Biomedical waste derived extract is also a panacea for treatment of various diseases. Placental therapy has been reported specifically to have potent action on recovery of diseases and tissue regeneration. Placental bioactive components and their multi targeting identity prompted us to compile the précised information on placental extract products. However, some findings are needed to be explored by scientific community to prove their clinical potential with clinically significant statistical conclusions. In the light of available information and the usefulness of the placental extract, it is necessary for the development of various formulations for various unmet meet for the treatment as well as access their adverse effects as well as contradictions and precisely evaluated in the short and in the long-term periods.


2016 ◽  
Author(s):  
Matthew G. Powell ◽  
◽  
Ian-Michael Taylor-Benjamin

Author(s):  
Carl N. Keiser ◽  
James L.L. Lichtenstein ◽  
Colin M. Wright ◽  
Gregory T. Chism ◽  
Jonathan N. Pruitt

The field of animal behavior has experienced a surge of studies focusing on functional differences among individuals in their behavioral tendencies (‘animal personalities’) and the relationships between different axes of behavioral variation (‘behavioral syndromes’). Many important developments in this field have arisen through research using insects and other terrestrial arthropods, in part, because they present the opportunity to test hypotheses not accessible in other taxa. This chapter reviews how studies on insects and spiders have advanced the study of animal personalities by describing the mechanisms underlying the emergence of individual variation and their ecological consequences. Furthermore, studies accounting for animal personalities can expand our understanding of phenomena in insect science like metamorphosis, eusociality, and applied insect behavior. In addition, this chapter serves to highlight some of the most exciting issues at the forefront of our field and to inspire entomologists and behaviorists alike to seek the answers to these questions.


1992 ◽  
Vol 6 (2) ◽  
pp. 719-723 ◽  
Author(s):  
Ulrich M. Zanger ◽  
Norio Kagawa ◽  
Johan Lund ◽  
Michael R. Waterman

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